SARS-CoV RBDs – Communicable Diseases Research

Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19

코로나19 중증도에 따라 항체 표적 SARS-CoV-2 에피토프 레퍼토리 달라

Article

Published on 2022-12-012022-09-11
Journal: Virulence
[Category] COVID19(2023년), SARS, 진단, 치료법,

[키워드] antibodies antibody Antigen association Asymptomatic asymptomatic individual asymptomatic infection betacoronavirus Betacoronavirus Community convalescent correlated COVID-19 COVID-19 severity develop diagnosed diagnostics disease severity domains Epitopes Evidence evidence of finding FIVE five groups HKU1 Hospitalization IgG IgGs Immunity immunogenic immunogenic peptide individual Infection less MERS-CoV nucleocapsid protein Nucleocapsid proteins OC43 participant pathogenic pathogenic mechanisms peptide peptide array peptides pilot study predicted Protein RBDs reaction Receptor binding domain Region repertoire SARS-CoV RBD SARS-CoV RBDs SARS-CoV-2 SARS-CoV-2 epitope SARS-CoV-2 epitopes seroconverted Seroprevalence seroprevalence. severity severity of COVID-19 symptomatic symptomatic COVID-19 symptomatic infection therapeutic therapeutic antibodies Vaccines Viral with COVID-19 without symptoms
[DOI] 10.1080/21505594.2022.2073025 PMC 바로가기 [Article Type] Article

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

교차 중화 항체의 조합은 SARS-CoV-2 및 SARS-CoV 슈도바이러스 감염을 예방하기 위해 상승합니다.

Article

Published on 2021-05-122022-09-10
Journal: Cell Host & Microbe
[Category] MERS, SARS, 변종, 진단,

[키워드] 3D structure Abstract antibodies antibody antibody cocktail antibody-antigen interaction antigenic antigenic drift antigenic variation B.1.1.7 B.1.351 bind bound waters caused circulating variant circulating variants Combination complex conserved coronavirus coronavirus disease Coronavirus disease 2019 COVA1-16 COVID-19 COVID-19 patient CR3022 cross-neutralizing cross-neutralizing antibodies cross-neutralizing antibody cross-react cross-reactivity crystal structure crystal structures Crystallography Effectiveness ENhance Epidemics facilitate glycan glycosylation site Infection information interact Interaction neutralization neutralize Neutralizing antibodies Pandemics Prevent PROTECT provide receptor-binding domains Recognition related viruses S309 Sarbecoviruses SARS-CoV SARS-CoV pseudovirus SARS-CoV RBD SARS-CoV RBDs SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-related coronaviruses SARS-related virus SARS-related viruses shown spike spikes Structure synergy the receptor-binding domain therapeutic therapeutic antibodies these viruses threat Threats Vaccine viruses X-ray zoonotic
[DOI] 10.1016/j.chom.2021.04.005 PMC 바로가기 [Article Type] Article